Main AHCA Website

AHCA’s main website for information on Medicaid, Health Quality Assurance and the Florida Center for Health Information and Transparency.

Go >

Florida Health Information Network

This website provides information and resources relating to AHCA’s initiatives for Health Information Technology and Health Information Exchange.

Go >


FloridaHealthFinder.gov

Provides health education and information to compare and locate health care providers in Florida to make well-informed health care decisions.

Go >
AHCA Network of Websites

Health Education


Health Encyclopedia

Search the Health Encyclopedia

Antimitochondrial antibody

Definition

Antimitochondrial antibodies (AMA) are substances (antibodies) that form against mitochondria. The mitochondria are an important part of cells. They are the energy source inside the cells and help the cells work properly.

This article discusses the blood test used to measure the amount of AMA in the blood.

How the Test is Performed

A blood sample is needed. It is most often taken from a vein. The procedure is called a venipuncture.

How to Prepare for the Test

Your health care provider may tell you not to eat or drink anything for up to 6 hours before the test (most often overnight).

How the Test will Feel

When the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.

Why the Test is Performed

You may need this test if you have signs of liver damage. This test is most often used to diagnose primary biliary cirrhosis (PBC).

The test may also be used to tell the difference between bile system-related cirrhosis and liver problems due to other causes such as a blockage, viral hepatitis, or alcoholic cirrhosis.

Normal Results

Normally, there are no antibodies present.

What Abnormal Results Mean

This test is important for diagnosing PBC. Almost all people with the condition will test positive. It is rare that a person without the condition will have a positive result.

Abnormal results may also be found, less often, in people with other kinds of liver disease and some autoimmune diseases.

Risks

Risks for having blood drawn are slight but can include:

  • Excessive bleeding
  • Fainting or feeling lightheaded
  • Hematoma (blood accumulating under the skin)
  • Infection (a slight risk any time the skin is broken)

References

Angulo P, Lindor KD. Primary biliary cirrhosis. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger & Fordtran's Gastrointestinal and Liver Disease. 9th ed. Philadelphia, PA: Elsevier Saunders; 2010:chap 89.

Muratori L, Granito A, Muratori P, et al. Antimitochondrial antibodies and other antibodies in primary biliary cirrhosis: diagnostic and prognostic value. Clin Liver Dis. 2008;12:261. PMID: 18456179 www.ncbi.nlm.nih.gov/pubmed/18456179.

Review Date:1/20/2015
Reviewed By:Gordon A. Starkebaum, MD, Professor of Medicine, Division of Rheumatology, University of Washington School of Medicine, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997-A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

adam.com

The Agency for Health Care Administration (Agency) and this website do not claim the information on, or referred to by, this site is error free. This site may include links to websites of other government agencies or private groups. Our Agency and this website do not control such sites and are not responsible for their content. Reference to or links to any other group, product, service, or information does not mean our Agency or this website approves of that group, product, service, or information.

Additionally, while health information provided through this website may be a valuable resource for the public, it is not designed to offer medical advice. Talk with your doctor about medical care questions you may have.

Health
Outcome Data

No data available for this condition/procedure.

Images

Health Encyclopedia

More Features

We Appreciate Your Feedback
1. Did you find this information useful?
         Yes
         No

2. Would you recommend this website to family and friends?
         Yes
         No