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Post-splenectomy syndrome

Definition

Post-splenectomy syndrome can occur after surgery to remove the spleen. It consists of a group of symptoms and signs such as:

  • Destruction of red blood cells
  • Increased risk of severe infections, from bacteria such as Streptococcus pneumoniae and Neisseria meningitidis
  • Thrombocytosis (increased platelet count, which can cause blood clots)

Alternative Names

Splenectomy - post-surgery syndrome

Possible Complications

Possible long-term medical problems include:

References

Connell NT, Shurin SB, Schiffman FJ. The spleen and its disorders. In: Hoffman R, Benz EJ Jr, Silberstein LE, Heslop HE, Weitz JI, Anastasi J, eds. Hematology: Basic Principles and Practice. 6th ed. Philadelphia, PA: Elsevier Saunders; 2013:chap 162.

Review Date:2/13/2015
Reviewed By:Rita Nanda, MD, Assistant Professor of Medicine, Section of Hematology/Oncology, University of Chicago Medicine, Chicago, IL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.

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Outcome Data

No data available for this condition/procedure.

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