Main AHCA Website

AHCA’s main website for information on Medicaid, Health Quality Assurance and the Florida Center for Health Information and Transparency.

Go >

Florida Health Information Network

This website provides information and resources relating to AHCA’s initiatives for Health Information Technology and Health Information Exchange.

Go >

Provides health education and information to compare and locate health care providers in Florida to make well-informed health care decisions.

Go >
AHCA Network of Websites

Health Education

Health Encyclopedia

Search the Health Encyclopedia

Lymphogranuloma venereum


Lymphogranuloma venereum (LGV) is a sexually transmitted bacterial infection.

Alternative Names

LGV; Lymphogranuloma inguinale; Lymphopathia venereum


Lymphogranuloma venereum (LGV) is a long-term (chronic) infection of the lymphatic system. It is caused by any of 3 different types (serovars) of the bacteria Chlamydia trachomatis. The bacteria are spread by sexual contact. The infection is not caused by the same bacteria that cause genital chlamydia.

LGV is more common in Central and South America than in North America.

LGV is more common in men than women. The main risk factor is being HIV-positive.


Symptoms of LGV can begin a few days to a month after coming in contact with the bacteria. Symptoms include:

  • Drainage through the skin from lymph nodes in the groin
  • Painful bowel movements (tenesmus)
  • Small painless sore on the male genitals or in the female genital tract
  • Swelling and redness of the skin in the groin area
  • Swelling of the labia (in women)
  • Swollen groin lymph nodes on one or both sides; it may also affect lymph nodes around the rectum in people who have anal intercourse
  • Blood or pus from the rectum (blood in the stools)

Exams and Tests

The health care provider will examine you and ask about your medical and sexual history. Tell your provider if you had sexual contact with someone you think has had symptoms of LGV.

A physical exam may show:

  • An oozing, abnormal connection (fistula) in the rectal area
  • A sore on the genitals
  • Drainage through the skin from lymph nodes in the groin
  • Swelling of the vulva or labia in women
  • Swollen lymph nodes in the groin (inguinal lymphadenopathy)

Tests may include:

  • Biopsy of the lymph node
  • Blood test for the bacteria that causes LGV
  • Laboratory test to detect chlamydia


LGV is treated with antibiotics, including doxycycline and erythromycin.

Outlook (Prognosis)

With treatment, the outlook is good.

Possible Complications

Health problems that may result from LVG infection include:

  • Abnormal connections between the rectum and vagina (fistula)
  • Brain inflammation (encephalitis - very rare)
  • Infections in the joints, eyes, heart, or liver
  • Long-term inflammation and swelling of the genitals
  • Scarring and narrowing of the rectum

Complications can occur many years after you are first infected.

When to Contact a Medical Professional

Call your provider if:

  • You have been in contact with someone who may have a sexually transmitted infection, including LGV
  • You develop symptoms of LGV


Not having any sexual activity is the only way to prevent a sexually transmitted infection. Safer sex behaviors may reduce the risk.

The proper use of condoms, either the male or female type, greatly decreases the risk of catching a sexually transmitted infection. You need to wear the condom from the beginning to the end of each sexual activity.


Batteiger BE, Tan M. Chlamydia trachomatis (trachoma, genital Infections, perinatal infections, and lymphogranuloma venereum). In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 8th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 182.

Eckert LO, Lentz GM. Infections of the lower and upper genital tracts: vulva, vagina, cervix, toxic shock syndrome, endometritis, and salpingitis. In: Lentz GM, Lobo RA, Gershenson DM, Katz VL, eds. Comprehensive Gynecology. 6th ed. Philadelphia, PA: Elsevier Mosby; 2012:chap 23.

Review Date:9/10/2015
Reviewed By:Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997-A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

The Agency for Health Care Administration (Agency) and this website do not claim the information on, or referred to by, this site is error free. This site may include links to websites of other government agencies or private groups. Our Agency and this website do not control such sites and are not responsible for their content. Reference to or links to any other group, product, service, or information does not mean our Agency or this website approves of that group, product, service, or information.

Additionally, while health information provided through this website may be a valuable resource for the public, it is not designed to offer medical advice. Talk with your doctor about medical care questions you may have.

Outcome Data

No data available for this condition/procedure.

Health Encyclopedia

More Features

We Appreciate Your Feedback
1. Did you find this information useful?

2. Would you recommend this website to family and friends?