Health Encyclopedia

Lung needle biopsy

Definition

A lung needle biopsy is a method to remove a piece of lung tissue for examination.

Alternative Names

Transthoracic needle aspiration; Percutaneous needle aspiration

How the test is performed

A chest x-ray or chest CT scan may be used to locate the precise spot of the biopsy. If the biopsy is done using a CT scan, you may be lying down during the exam.

A needle biopsy of the lung may also be performed during bronchoscopy or mediastinoscopy.

You sit with your arms resting forward on a table. You should try to keep still and not cough during the biopsy. The doctor will ask you to hold your breath. The skin is scrubbed and a local anesthetic is injected.

The surgeon will make a small (about 1/8-inch) cut in the skin, and will insert the biopsy needle into the abnormal tissue, tumor, or lung tissue. A small piece of tissue is removed with the needle and sent to a laboratory for examination.

When done, pressure is placed over the site. Once bleeding has stopped, a bandage is applied.

A chest x-ray is taken immediately after the biopsy.

The procedure usually takes 30 - 60 minutes. Laboratory analysis usually takes a few days.

How to prepare for the test

Before a needle biopsy of the lung is conducted, a chest x-ray or chest CT scan may be performed. Sometimes, you will be given a mild sedative before the biopsy. You must sign a consent form. It is important to remain as still as possible for the biopsy and to avoid coughing.

How the test will feel

A lung needle biopsy is preceded by a local injection of anesthetic, which will sting for a moment. You will feel pressure and a brief, sharp pain when the needle touches the lung.

Why the test is performed

A needle lung biopsy is performed when there is an abnormal condition that is near the surface of the lung, in the lung itself, or on the chest wall. The test is usually performed to diagnose relatively large abnormalities seen on chest x-ray or CT scan. Most often, the abnormality is not believed to be accessible by other diagnostic techniques, such as bronchoscopy.

Normal Values

Normal tissues and no microbial growth, if a culture is performed, are normal.

What abnormal results mean

Bacterial, viral, or fungal lung infection
Pneumonia
Cancerous cells (lung cancer, mesothelioma)
Immune disorder

Additional conditions under which the test may be performed:

What the risks are

The risks include a collapsed lung, bleeding, and infection.

A needle biopsy should NOT be performed if other tests show that you have:

Bullae (enlarged alveoli associated with emphysema)
Cysts
Blood coagulation disorder of any type
Severe hypoxia
Pulmonary hypertension
Cor pulmonale

Special considerations

Signs of a collapsed lung include:

If any of these occur, report them to the health care provider immediately.

Review Date:1/16/2008
Reviewed By:David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc. Previously reviewed by David A. Kaufman, M.D., Assistant Professor, Division of Pulmonary, Critical Care & Sleep Medicine, Mount Sinai School of Medicine, New York, NY. Review provided by VeriMed Healthcare Network (11/13/2006).

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