Health Encyclopedia

Urine concentration test

Definition

A urine concentration test measures the ability of the kidneys to conserve or excrete water appropriately.

Alternative Names

Water loading test; Water deprivation test

How the test is performed

For this test, the specific gravity of urine is measured before and after one or more of the following:

Water loading -- drinking excessive amounts of water or receiving fluids through a vein
Water deprivation -- avoiding fluids for a certain amount of time
ADH adminitration -- receiving antidiuretic hormone (ADH), which should cause the urine to become concentrated

The test requires a clean-catch urine sample.

To obtain a clean-catch sample, men or boys should clean the head of the penis. Women or girls need to wash the area between the lips of the vagina with soapy water and rinse well.

As you start to urinate, allow a small amount to fall into the toilet bowl to clear the urethra of contaminants. Then, put a clean container under your urine stream and catch 1 to 2 ounces of urine. Remove the container from the urine stream. Cap and mark the container and give it to the health care provider or assistant.

For infants, thoroughly wash the area around the urethra. Open a urine collection bag (a plastic bag with an adhesive paper on one end), and place it on the infant. For boys, the entire penis can be placed in the bag and the adhesive attached to the skin. For girls, the bag is placed over the labia. Diaper as usual over the secured bag.

This procedure may take a couple of attempts -- lively infants can displace the bag. The infant should be checked frequently and the bag changed after the infant has urinated into the bag. The urine is drained into the container for transport to the laboratory.

How to prepare for the test

Eat a normal, balanced diet for several days before the test. Your health care provider will give you instructions for water loading or water deprivation.

Your health care provider will instruct you, if necessary, to discontinue drugs that may interfere with the test. Drugs that can affect measurements include dextran and sucrose, and x-ray contrast medium (dye) received within 3 days.

How the test will feel

The test involves only normal urination, and there is no discomfort.

Why the test is performed

This test is most often done if your doctor suspects diabetes insipidus . The test can help tell differentiate it from nephrogenic diabetes insipidus.

This test may also be done if you have signs of SIADH (syndrome of inappropriate ADH ).

Normal Values

In general, normal values are as follows:

1.010 to 1.025 (normal specific gravity)
1.001 after drinking excessive amounts of water
More than 1.025 after avoiding fluids
Concentrated after receiving ADH

Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.

What abnormal results mean

Increased urine concentration may indicate:

Dehydration
Diarrhea
Excessive sweating
Glucosuria
Heart failure (related to decreased blood flow to the kidneys)
Renal arterial stenosis
Syndrome of inappropriate antidiuretic hormone secretion (SIADH)
Vomiting
Water restriction

Decreased urine concentration may indicate:

Excessive fluid intake
Diabetes insipidus
Renal failure (loss of ability to reabsorb water)
Pyelonephritis

Additional conditions under which the test may be performed:

Complicated UTI (pyelonephritis)
Nephrogenic diabetes insipidus

Review Date:10/22/2007
Reviewed By:Robert Mushnick, M.D., Clinical Assistant Professor, Department of Nephrology, SUNY Downstate Health Center, Brooklyn, NY. Review provided by VeriMed Healthcare Network.

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