Health Encyclopedia

Biopsy - polyps

Definition

A polyp biopsy is a diagnostic procedure that removes polyps (abnormal growths of tissue that may be cancerous) for examination.

Alternative Names

Polyp biopsy

How the test is performed

Polyps are outgrowths of tissue that may be attached by a pedicle. They are commonly found in organs with many blood vessels, such as the uterus, rectum, and nose. Some polyps are cancerous (malignant) and likely to spread, while others are non-cancerous (benign).

How a polyp biopsy is taken depends on the location:

EGD (esophagogastroduodenoscopy) or other endoscopy is used for the throat, stomach and small bowel.
Colonoscopy or flexible sigmoidoscopy explores the large bowel.
Colposcopy-directed biopsy examines the vagina and cervix

For areas of the body that are visible, a topical anesthetic is applied, and a small piece of the tissue that appears to be abnormal is removed. This tissue is sent to the laboratory, where technicians determine if the polyp is benign or malignant.

How to prepare for the test

If the biopsy is to take place in the nose, or other visible surface or orifice, no special preparation is required, although fasting for a few a hours may be advisable.

There is more involved preparation for internal procedures. Please see the particular procedure for additional information.

How the test will feel

For superficial polyps, you may feel a tugging sensation while the biopsy is being taken. After the anesthetic wears off, the area may be sore for a few days. Biopsies of internal polyps are performed during procedures (for example EGD or colonoscopy), and usually nothing is felt during or after the biopsy. Please see the individual procedure topics for more specific information.

Why the test is performed

The test is performed to determine if the growth is malignant.

Normal Values

The biopsy examination shows the polyp to be benign.

What abnormal results mean

Malignant cells are present and may indicate a malignant tumor. Further tests may be needed.

What the risks are

Risks include:

Organ perforation
Infection
Bleeding

Review Date:5/8/2006
Reviewed By:Jenifer K. Lehrer, MD, Department of Gastroenterology, Frankford-Torresdale Hospital, Jefferson Health System, Philadelphia, PA. Review provided by VeriMed Healthcare Network.

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