Health Encyclopedia

Muscle atrophy

Definition

Muscle atrophy refers to the wasting or loss of muscle tissue resulting from disease or lack of use.

Alternative Names

Muscle wasting; Wasting; Atrophy of the muscles

Considerations

There are two types of muscle atrophy.

Disuse atrophy occurs from a lack of physical exercise. The majority of muscle atrophy in the general population results from disuse. Persons with sedentary jobs, with medical conditions that limit movement, or who have decreased activity levels can lose muscle tone and develop atrophy. This type of atrophy can be reversible with vigorous exercise.

Bed-ridden people can undergo significant muscle wasting. Astronauts, free of the gravitational pull of Earth, can develop decreased muscle tone and loss of calcium from their bones following just a few days of weightlessness.

The most severe type of muscle atrophy is neurogenic atrophy. It occurs when there is injury or disease to a nerve. This type of muscle atrophy tends to occur more suddenly than disuse atrophy.

Examples of diseases affecting the nerves that control muscles would be poliomyelitis (polio), amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease), and Guillain-Barre syndrome.

Even minor muscle atrophy usually results in some loss of mobility or power.

Common Causes

Some atrophy occurs normally with aging. Other causes may include:

Amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease)
Burns
Diabetic neuropathy
Guillain-Barre syndrome
Injury
Long-term corticosteroid therapy
Long-term immobilization
Muscular dystrophy
Osteoarthritis
Rheumatoid arthritis
Peripheral neuropathy
Polio
Spinal cord injury
Stroke

Home Care

An exercise program (under the direction of a therapist or doctor) is recommended along with whirlpool baths and other types of rehabilitation.

Exercises using braces or splints are recommended for those who cannot actively move one or more joints.

Call your health care provider if

Call your doctor for an appointment if you have unexplained or prolonged loss of muscle.

What to expect at your health care provider's office

The doctor will perform a physical examination and ask questions about your medical history and symptoms, including

When did the muscle atrophy begin?
Is it getting worse?
What nerve or muscle is affected?
What other symptoms do you have?

The doctor will look at your arms and legs and measure muscle size.

Tests that may be performed include:

Treatment may include ultrasound therapy and, in some cases, surgery to correct a contracture.

Review Date:5/22/2007
Reviewed By:Joseph V. Campellone, M.D., Division of Neurology, Cooper University Hospital, Camden, NJ. Review provided by VeriMed Healthcare Network.

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